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Updated: Mar 28, 2026
Intracranial Orthotopic Allografting of Medulloblastoma Cells in Immunocompromised Mice
Published on: October 3, 2010
[Adult medulloblastoma: Retrospective series of 21 patients]
C Vigneron1, D Antoni1, A Coca2
1Département de radiothérapie, centre Paul-Strauss, 3, rue de la Porte-de-l'Hôpital, 67000 Strasbourg, France.
Purpose:
Retrospective analysis of the results of 21 adults treated for medulloblastoma.
Patients And Methods:
Between 1978 and 2011, 21 adults with an average age of 31 years (18.3-50) were treated with surgery then with radiotherapy (n=20) at the Comprehensive Cancer Center of Strasbourg. For some (n=12), treatment consisted of chemotherapy.
Results:
After a mean follow-up of 122 months (19-423), six relapses and seven deaths were observed. Overall survival at 5 years and 10 years was 89.4 ± 7.1% for both. Disease-free survival at 5 years and 10 years was 79.6 ± 9.2% and 85.7 ± 7.6% and 60.6 ± 17.7%, respectively.
Conclusion:
The rarity of medulloblastoma, especially in adults and these results confirm the necessity of international protocols.
