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Transformation of an active pharmaceutical ingredient upon high-energy milling: A process-induced disorder in

Benjamin Schammé1, Nicolas Couvrat2, Pascal Malpeli3

  • 1Normandie Univ, Laboratoire SMS-EA3233, Univ Rouen, F-76821 Mont Saint Aignan, France; Normandie Univ, AMME-LECAP EA 4528 International Lab, Univ Rouen, Avenue de l'Université, BP12, F-76801 Saint Etienne du Rouvray, France.

International Journal of Pharmaceutics
|December 29, 2015
PubMed

Keywords:
AmorphousBiclotymolBiclotymol (PubChem CID71878)Glass transitionMillingPharmaceuticalsPolyvinylpyrrolidonePolyvinylpyrrolidone (PubChem CID6917)Stability

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