[Apixaban in the treatment of venous thrombosis associated with permanent pacemaker implantation]

Sebastián Carrizo1, Jorge A Figueroa, Alejandro Vivero

  • 1Servicio de Cardiología, Sanatorio de la Cañada, Córdoba, Argentina.

Medicina
|December 29, 2015
PubMed

Insights

New oral anticoagulants like apixaban offer a safe alternative for venous thromboembolism. This case study shows successful treatment of superficial venous thrombosis in an elderly patient with apixaban.

Area of Science:

  • Cardiology
  • Vascular Medicine
  • Pharmacology

Background:

  • Venous thromboembolism (VTE) is a significant cause of vascular disease morbidity and mortality.
  • Newer oral anticoagulants (NOACs) are emerging as effective and safe alternatives to traditional antithrombotic treatments.
  • Apixaban is a recently approved NOAC for treating deep vein thrombosis.

Observation:

  • An elderly patient presented with superficial venous thrombosis in the arm ipsilateral to a recent pacemaker implant.
  • The patient had a high risk of bleeding and a history of cancer.

Findings:

  • The patient was successfully treated with apixaban.
  • Apixaban demonstrated efficacy in managing superficial venous thrombosis in a complex patient profile.

Implications:

  • This case highlights the potential utility of apixaban in managing venous thromboembolism, even in high-risk patients.
  • Apixaban may be a viable therapeutic option for superficial venous thrombosis, offering a favorable safety profile.
  • Further research into apixaban's role in diverse VTE presentations is warranted.

Related Concept Videos

Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
463
ECG Interpretation of Arrhythmias II: Atrial, Junctional and Ventricular Arrhythmias01:25

ECG Interpretation of Arrhythmias II: Atrial, Junctional and Ventricular Arrhythmias

Arrhythmia is a condition characterized by an irregular heart rhythm, with ECG changes that differ based on its origin and nature. The types of arrhythmias discussed below include atrial, junctional, and ventricular arrhythmias.Atrial ArrhythmiasPremature Atrial Complexes (PACs): PACs are early atrial beats caused by stress, caffeine, alcohol, electrolyte imbalances, hypoxia, hyperthyroidism, or certain medications (e.g., bronchodilators and decongestants). The ECG shows early P waves with an...
926
Endocarditis IV: Nursing Management01:29

Endocarditis IV: Nursing Management

Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
566
Dysrhythmias VI: Management of Dysrhythmias01:25

Dysrhythmias VI: Management of Dysrhythmias

Dysrhythmia management involves a multifaceted approach, incorporating pharmacological treatments, medical procedures, surgical interventions, lifestyle modifications, and patient education.Pharmacological ManagementAntiarrhythmic Drugs:Class I (Sodium Channel Blockers): This class includes quinidine and procainamide, which reduce the speed of impulse conduction in the heart, stabilize the cardiac membrane, and control arrhythmias. Quinidine and procainamide are Class IA agents that prolong the...
613
Anticoagulant Drugs: Low-Molecular-Weight Heparins01:30

Anticoagulant Drugs: Low-Molecular-Weight Heparins

Hemostasis is a crucial process that prevents excessive blood loss from damaged blood vessels. It involves various mechanisms such as vasoconstriction, platelet adhesion and activation, and fibrin formation. The importance of each mechanism depends on the type of vessel injury. In contrast, thrombosis is the abnormal formation of a blood clot within the blood vessels, leading to potential complications if the clot obstructs blood flow. Thrombosis can be caused by increased coagulability of the...
2.3K
Peripheral Artery Disease III: Interprofessional Care01:27

Peripheral Artery Disease III: Interprofessional Care

Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
547