Eosinophilic colitis under etanercept.

Area of Science:

• Gastroenterology
• Immunology

Background:

• Eosinophilic colitis (EC) is a rare eosinophilic gastrointestinal disorder.
• Histopathological examination is crucial for EC diagnosis, despite unclear eosinophil cut-offs.
• Corticosteroids are the primary treatment for EC.

Observation:

• A woman diagnosed with eosinophilic colitis presented with symptoms.
• Initial treatment with budesonide led to clinical remission.

Findings:

• The patient's condition was successfully maintained solely with adalimumab after budesonide therapy.
• This suggests a potential steroid-sparing maintenance strategy for EC.

Implications:

• Adalimumab may offer a viable long-term, steroid-sparing option for eosinophilic colitis management.
• Further research into biologic therapies for EC is warranted.