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Updated: Mar 28, 2026

Preparation of Neuronal Co-cultures with Single Cell Precision
Published on: May 20, 2014
Mobile Microplates for Morphological Control and Assembly of Individual Neural Cells
Shotaro Yoshida1, Tetsuhiko Teshima1, Kaori Kuribayashi-Shigetomi1
1Center for International Research on Integrative Biomedical Systems, Institute of Industrial Science, The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo, 153-8505, Japan.
Abstract:
A microfabricated device that enables morphological control and assembly of cultured single neural cells is described. Assembly of morphologically controlled single neural cells allows neuroengineers to design in vitro neural circuits with a single-cell resolution. Compared to conventional cell-patterning techniques, the device allows for the highly precise positioning of neural somas and neurites in a reproducible fashion.
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