Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

X-ray Crystallography

X-ray Crystallography

The size of the unit cell and the arrangement of atoms in a crystal may be determined from measurements of the diffraction of X-rays by the crystal, termed X-ray crystallography.
Diffraction
Diffraction is the change in the direction of travel experienced by an electromagnetic wave when it encounters a physical barrier whose dimensions are comparable to those of the wavelength of the light. X-rays are electromagnetic radiation with wavelengths about as long as the distance between neighboring...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Lifetime and acute risk of suicidality by profiles of early life adversity: an observational cohort study in a high-risk population.

Scientific reports·2026

Same author

Diagnostic value of basic and extended procedures in pediatric fever of unknown origin - results of a nation-wide surveillance study.

Molecular and cellular pediatrics·2026

Same author

Advanced X-Ray Imaging Technology.

Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer·2026

Same author

Changes of borderline symptoms, personality functioning, and dysfunctional personality traits after dialectical-behavioral therapy in borderline personality disorder.

European archives of psychiatry and clinical neuroscience·2026

Same author

Beam-hardening correction in clinical x-ray dark-field chest radiography using deep-learning-based bone segmentation.

Medical physics·2026

Same author

Efficacy, moderators and mediators of cognitive behavioural analysis system of psychotherapy (CBASP) versus behavioural activation (BA) in persistently depressed treatment-resistant inpatients: study protocol for the multicentre, randomised controlled <i>changePDD</i> trial.

BMJ open·2026

Same journal

Generalizable framework for multi-site bone density prediction using non-dominant wrist optical biomarkers.

Biomedical optics express·2026

Same journal

Erratum: Review of dynamic optical coherence tomography for intracellular motility [Invited]: errata.

Biomedical optics express·2026

Same journal

Digital-micromirror-device-based illumination strategies for background suppression in single-molecule localization microscopy.

Biomedical optics express·2026

Same journal

Synergistic combination of convective self-assembly and hollow core fiber for sensitive SERS detection of glucose molecules.

Biomedical optics express·2026

Same journal

Multimodal diagnostic network integrating infrared and mass spectra for lung cancer.

Biomedical optics express·2026

Same journal

Multimodal Optical Biosensing for Precision Medicine and Healthcare: Introduction to the feature issue.

Biomedical optics express·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Mar 28, 2026

Measurement of X-ray Beam Coherence along Multiple Directions Using 2-D Checkerboard Phase Grating

Measurement of X-ray Beam Coherence along Multiple Directions Using 2-D Checkerboard Phase Grating

Published on: October 11, 2016

Lens-term- and edge-effect in X-ray grating interferometry.

Johannes Wolf¹, Jonathan I Sperl², Florian Schaff¹

¹Lehrstuhl für Biomedizinische Physik, Physik-Department & Institut für Medizintechnik, Technische Universität München, 85748 Garching, Germany.

Biomedical Optics Express

|December 30, 2015

Summary

This summary is machine-generated.

This study explains how mismatches in X-ray grating interferometry affect dark-field contrast. Understanding wave-front curvature is key to interpreting dark-field signals from object edges.

Keywords:

(110.7440) X-ray imaging (340.7450) X-ray interferometry

More Related Videos

The Generation of Higher-order Laguerre-Gauss Optical Beams for High-precision Interferometry

The Generation of Higher-order Laguerre-Gauss Optical Beams for High-precision Interferometry

Published on: August 12, 2013

Spectral and Angle-Resolved Magneto-Optical Characterization of Photonic Nanostructures

Spectral and Angle-Resolved Magneto-Optical Characterization of Photonic Nanostructures

Published on: November 21, 2019

Related Experiment Videos

Last Updated: Mar 28, 2026

Measurement of X-ray Beam Coherence along Multiple Directions Using 2-D Checkerboard Phase Grating

Measurement of X-ray Beam Coherence along Multiple Directions Using 2-D Checkerboard Phase Grating

Published on: October 11, 2016

The Generation of Higher-order Laguerre-Gauss Optical Beams for High-precision Interferometry

The Generation of Higher-order Laguerre-Gauss Optical Beams for High-precision Interferometry

Published on: August 12, 2013

Spectral and Angle-Resolved Magneto-Optical Characterization of Photonic Nanostructures

Spectral and Angle-Resolved Magneto-Optical Characterization of Photonic Nanostructures

Published on: November 21, 2019

Area of Science:

Physics
Materials Science
Medical Imaging

Background:

X-ray grating interferometry utilizes micrometer-period gratings for dark-field contrast acquisition.
Accurate matching between the analyzer grating and interference pattern is crucial for signal detection.

Purpose of the Study:

To investigate the impact of sample-induced period mismatches on dark-field contrast in X-ray grating interferometry.
To develop a formula for calculating the signal generated by period mismatches.
To elucidate the role of wave-front curvature in altering interference pattern periods.

Main Methods:

Theoretical analysis and development of a formula for period mismatch signal calculation.
Numerical simulations of X-ray wave-front propagation.
Parametric estimations involving grating periods and detector pixel size.

Main Results:

A formula was proposed to quantify the signal arising from period mismatches.
Numerical simulations confirmed that wave-front curvature (lens-term) alters interference pattern periods.
The study provides a clear explanation for dark-field contrast formation at object edges.

Conclusions:

Wave-front curvature, such as from parabolic lenses or sample edges, can modify interference pattern periods.
This research enhances the understanding of dark-field signal generation in grating interferometry.
The findings are crucial for optimizing imaging techniques and interpreting results in X-ray microscopy and diagnostics.