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Prediction of the anti-inflammatory mechanisms of curcumin by module-based protein interaction network analysis

Yanxiong Gan1, Shichao Zheng2, Jan P A Baak3

  • 1State Key Laboratory Breeding Base of Systematic Research, Development and Utilization of Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.

Acta Pharmaceutica Sinica. B
|December 30, 2015
PubMed

Keywords:
Anti-inflammatoryCurcuminCytoscapeETS, erythroblast transformation-specificGO, gene ontologyGene ontology  enrichment analysisIFNs, interferonsIL, interleukinJAK-STAT, Janus kinase-STATMAPK, mitogen-activated protein kinaseMCODE, molecular complex detectionModuleMolecular complex  detectionMolecular mechanismNF-κB, nuclear factor kappa BPIN, protein interaction networkPPIs, protein–protein interactionsProtein interaction  networkSTATs, signal transducer and activator of transcription complexesTLR, toll-like receptor

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