Related Experiment Video
Updated: Mar 28, 2026

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats
Published on: April 4, 2025
Infective Endocarditis and Chronic Kidney Disease: How to Deal with Complications
Yusra Habib Khan1, Azmi Sarriff1, Amer Hayat Khan1
1School of Pharmaceutical Sciences, Universiti Sains Malaysia, 11800 Pulau Pinang, Malaysia.
Insights
Infective endocarditis (IE) is a serious risk for hemodialysis patients, often linked to catheter use. This case highlights IE in a geriatric end-stage renal disease patient, emphasizing the need for vigilant infection management.
Area of Science:
- Nephrology
- Infectious Diseases
- Cardiology
Background:
- Infective endocarditis (IE) significantly increases mortality and morbidity in hemodialysis patients.
- Hemodialysis catheters are a primary risk factor for IE due to susceptibility to blood-borne infections.
- Geriatric patients with end-stage renal disease (ESRD) are particularly vulnerable.
Purpose of the Study:
- To present a case of nosocomial IE in a geriatric ESRD patient.
- To highlight the link between catheter-related infections and IE in hemodialysis patients.
- To emphasize the importance of managing comorbidities and infection.
Main Methods:
- Case report of a geriatric ESRD patient readmitted with IE symptoms.
- Clinical examination and review of medical history, including hypertension, diabetes mellitus, and ischemic heart disease.
- Diagnostic suspicion of IE secondary to catheter-related infection.
Main Results:
- The patient presented with symptoms consistent with nosocomial IE post-hemodialysis.
- Concurrent conditions included hypertension, diabetes mellitus, and ischemic heart disease.
- Catheter-related infection was suspected as the cause of IE.
Conclusions:
- IE poses a significant threat to hemodialysis patients, especially the elderly.
- Catheter use in hemodialysis increases the risk of IE.
- Comprehensive management of comorbidities and prompt infection treatment are crucial for patient outcomes.
Abstract:
Infective endocarditis (IE) is the one of the most important causes of increased mortality and morbidity among haemodialysis patients. The reason for this increasing prevalence of infection among these patients is the use of haemodialysis catheters during dialysis, as these patients are highly susceptible to infections that are easily transmitted via blood access points. The present case was a geriatric end stage renal disease (ESRD) patient who was readmitted to the hospital two days after her scheduled haemodialysis session with symptoms of nosocomial endocarditis. Her concurrent medical complications were hypertension, non-insulin dependent diabetes mellitus, and ischemic heart disease. Based on her previous medical history and current examination, the patient was suspected to have IE due to catheter related infection. The goal of therapy is to manage the comorbidities and infection by provision of appropriate treatment based on close monitoring of the patient condition.
Related Concept Videos
Chronic Kidney Disease III: Interprofessional Care
Endocarditis III: Medical Management
Chronic Kidney Disease IV: Nursing Management
Endocarditis IV: Nursing Management
Acute Kidney Injury V: Interprofessional Care
Chronic Kidney Disease I: Introduction

