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Related Concept Videos

Heart Failure II: Pathophysiology01:29

Heart Failure II: Pathophysiology

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Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
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Heart Failure V: Medical Management01:30

Heart Failure V: Medical Management

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Medical Management of Acute Decompensated Heart Failure (ADHF)The primary goals of therapy for patients hospitalized with acute decompensated heart failure (ADHF) include:Relieving symptomsOptimizing volume statusSupporting oxygenation and ventilationMaintaining cardiac output (CO) and end-organ perfusionIdentifying and addressing the cause of ADHFPreventing complicationsProviding patient education on factors precipitating HF exacerbationPlanning for dischargeOngoing monitoring and assessment...
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Pathophysiology of Heart Failure01:17

Pathophysiology of Heart Failure

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Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
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Heart Failure VII: Nursing Interventions01:30

Heart Failure VII: Nursing Interventions

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The first step in nursing management of a patient with heart failure involves thoroughly assessing the patient's medical history.Subjective Data: Obtain the patient's medical history of coronary artery disease, hypertension, myocardial infarction, and symptoms like dyspnea, orthopnea, and paroxysmal nocturnal dyspnea.Objective Data: Conduct a physical examination to identify findings such as jugular vein distention, pulmonary crackles, tachycardia, murmurs, peripheral edema, and vital signs,...
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Heart Failure IV: Classification and Diagnostic Evaluation01:30

Heart Failure IV: Classification and Diagnostic Evaluation

579
Heart failure can be classified in various ways, with the most common classifications based on physical activity limitations, disease progression, severity, and treatment strategies.The Functional Classification of Heart Failure divides patients into four categories based on physical activity limitation due to symptom burden.Class I: Patients in this class have cardiac disease but no physical activity limitations. Ordinary activities like walking, climbing stairs, or routine tasks do not cause...
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Heart Failure Drugs: Inhibitors of Renin-Angiotensin System01:26

Heart Failure Drugs: Inhibitors of Renin-Angiotensin System

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The activation of the sympathetic nervous system and the renin-angiotensin-aldosterone system (RAAS) contributes to cardiac remodeling, and inhibiting the RAAS is a pharmacological target in heart failure management. As a result, neurohumoral modulation is a crucial treatment principle for managing heart failure. This approach involves using medications like ACE inhibitors (ACEIs), angiotensin receptor blockers (ARBs), β-blockers, mineralocorticoid receptor antagonists (MRAs), and neutral...
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Related Experiment Video

Updated: Mar 28, 2026

Author Spotlight: Unveiling Prognostic Indicators in Heart Failure - The Role of Phase Angle and Bioelectrical Impedance Analysis
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Author Spotlight: Unveiling Prognostic Indicators in Heart Failure - The Role of Phase Angle and Bioelectrical Impedance Analysis

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Predicting outcome in acute heart failure, does it matter?

Leili Pourafkari, Samad Ghaffari, Ata H Afshar

    Acta Cardiologica
    |December 31, 2015
    PubMed
    Summary

    Acute heart failure (AHF) following acute coronary syndrome has a poor prognosis. Higher cardiac injury markers and white blood cell counts indicate worse outcomes in AHF patients.

    Keywords:
    Acute heart failurehospital length of staymortalityoutcome

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    Primary Outcome Assessment in a Pig Model of Acute Myocardial Infarction
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    Primary Outcome Assessment in a Pig Model of Acute Myocardial Infarction
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    Primary Outcome Assessment in a Pig Model of Acute Myocardial Infarction

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    Area of Science:

    • Cardiology
    • Internal Medicine
    • Critical Care Medicine

    Background:

    • Acute heart failure (AHF) is a serious condition with high mortality.
    • Heart failure post-coronary events has a particularly poor prognosis.
    • Predicting AHF outcomes is crucial for patient management.

    Purpose of the Study:

    • To predict in-hospital and long-term prognosis of AHF.
    • To identify key predictors of mortality in AHF patients.
    • To analyze the impact of comorbidities and clinical findings on AHF outcomes.

    Main Methods:

    • Retrospective review of 366 AHF patient charts over 4 years.
    • Collection of demographic, medical history, symptoms, and physical findings.
    • Analysis of laboratory markers, echocardiography, and angiography (where applicable).

    Main Results:

    • Acute coronary syndrome (STEMI/NSTEMI) was the strongest predictor of in-hospital death.
    • Older age, female gender, acute myocardial infarction markers (cTNI, CKMB), low blood pressure, low LVEF, and high WBC independently predicted long-term mortality.
    • Multivariate logistic regression identified significant prognostic factors.

    Conclusions:

    • AHF following acute coronary syndrome has a higher fatality rate.
    • Elevated cardiac injury markers and white blood cell counts suggest a poor prognosis in AHF.
    • Clinical factors at admission are vital for predicting AHF outcomes.