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Updated: Mar 28, 2026

Endoscopic Injection Sclerotherapy Assisted by Cyanoacrylate and Clips for Gastroesophageal Varices
Published on: June 13, 2025
Cap-assisted endoscopic sclerotherapy for hemorrhoids: Methods, feasibility and efficacy
Ting Zhang1, Li-Juan Xu1, Jie Xiang1
1Ting Zhang, Li-Juan Xu, Jie Xiang, Zhi He, Zhao-Yuan Peng, Guang-Ming Huang, Guo-Zhong Ji, Fa-Ming Zhang, Medical Center for Digestive Diseases, the Second Affiliated Hospital of Nanjing Medical University, Nanjing 210011, Jiangsu Province, China.
Cap-assisted endoscopic sclerotherapy (CAES) is a safe and effective new treatment for internal hemorrhoids. This pilot study found high patient satisfaction and no bleeding post-procedure.
Area of Science:
- Gastroenterology
- Endoscopic procedures
Background:
- Internal hemorrhoids affect a significant portion of the population.
- Current treatment options for internal hemorrhoids have varying success rates and potential complications.
Purpose of the Study:
- To evaluate the methodology, feasibility, safety, and efficacy of cap-assisted endoscopic sclerotherapy (CAES) for internal hemorrhoids.
- To assess patient satisfaction with the novel CAES procedure.
Main Methods:
- A pilot study involving 30 patients with grade I to III internal hemorrhoids was conducted.
- Colonoscopy with terminal ileum examination was performed prior to CAES.
- CAES was performed using a cap, endoscope, injection needle, insufflated air, and sclerosing agent. Polypectomy or anal papilla fibroma excision was done if indicated.
Main Results:
- No bleeding complications were observed post-CAES.
- One patient (3.33%) experienced mild tenesmus, attributed to the endoscopist's initial experience with the procedure.
- 100% of patients reported satisfaction with CAES, particularly when combined with other endoscopic resections.
Conclusions:
- Cap-assisted endoscopic sclerotherapy (CAES) is a convenient, safe, and effective flexible endoscopic therapy for internal hemorrhoids.
- The procedure demonstrates high patient satisfaction and a favorable safety profile.
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