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Updated: Mar 28, 2026
High-throughput Synthesis of Carbohydrates and Functionalization of Polyanhydride Nanoparticles
Published on: July 6, 2012
Automatic reactor for solid-phase synthesis of molecularly imprinted polymeric nanoparticles (MIP NPs) in water
Alessandro Poma1, Antonio Guerreiro1, Sarah Caygill1
1Cranfield Health, Cranfield University, Cranfield, MK43 0AL, United Kingdom.
Abstract:
We report the development of an automated chemical reactor for solid-phase synthesis of MIP NPs in water. Operational parameters are under computer control, requiring minimal operator intervention. In this study, "ready for use" MIP NPs with sub-nanomolar affinity are prepared against pepsin A, trypsin and α-amylase in only 4 hours.
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