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Discovery of highly potent dual EP(2) and EP(3) agonists with subtype selectivity

Akihiro Kinoshita1, Masato Higashino1, Yoshiyuki Aratani1

  • 1Medicinal Chemistry Research Laboratories, Ono Pharmaceutical Co., Ltd, 3-1-1 Sakurai, Shimamoto-cho, Mishima-gun, Osaka 618-8585, Japan.

Bioorganic & Medicinal Chemistry Letters
|January 5, 2016
PubMed

Keywords:
Dual agonistEP(2) receptorEP(3) receptorProstaglandinUnderactive bladder

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