Non-Enzymatic Glucose Sensor Based on 3D Graphene Oxide Hydrogel Crosslinked by Various Diamines

The non-enzymatic glucose sensor was fabricated by well-controlled and chemically crosslinked graphene oxide hydrogels (GOHs). By using various diamines such as ethylenediamine (EDA), p-phenylene diamine (pPDA) and o-phenylene diamine (oPDA) that have different amine to amine distance, we can control the structures of GOHs such as surface area and pore volume. The pPDA-GOH fabricated by pPDA exhibited the largest surface area and pore volume due to its longest amine to amine distance, which resulted in highest sensitivity in glucose and other monosaccharide sensing such as fructose (C6H12O6), galactose (C6H12O6) and sucrose (C12H22O11). It also showed fast and wide range glucose sensing ability in the amperometric test, and an excellent selectivity toward other interference species such as an Ascorbic acid.