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Perinatal complications associated with preterm deliveries at 24 to 33 weeks and 6 days gestation (2011- 2012): A
Maryam Khoshnood Shariati1, Zohreh Karimi2, Mahroo Rezaienejad3
1Neonatal Unit, Mahdiyeh Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Insights
Preterm birth before 34 weeks gestation significantly impacts infant outcomes. Key risk factors include preeclampsia and premature rupture of membranes, leading to high rates of neonatal mortality and morbidity such as sepsis and respiratory distress syndrome.
Area of Science:
- Perinatal Medicine
- Neonatalogy
- Obstetrics
Background:
- Preterm birth is a leading cause of neonatal mortality and morbidity in developed nations.
- Approximately 70% of neonatal mortality and 75% of morbidity are attributed to preterm delivery.
Purpose of the Study:
- To identify risk factors for preterm labor.
- To evaluate perinatal mortality and morbidity outcomes in infants born before 34 weeks gestation.
Main Methods:
- Retrospective study including infants born between 24 and 33 weeks and 6 days gestation.
- Data collected from November 2011 to March 2012.
Main Results:
- Preeclampsia (21%), premature rupture of membranes (20.3%), and placental abruption (10%) were major obstetrical risk factors.
- Neonatal mortality rate was 9.05% for infants under 34 weeks.
- Common morbidities included sepsis (46.94%), respiratory distress syndrome (41.47%), and patent ductus arteriosus (21.47%).
Conclusions:
- Preterm birth is linked to adverse perinatal outcomes.
- Enhanced prenatal health services and advanced neonatal care are crucial for improving outcomes.
Background:
Morbidity and mortality of preterm babies are important issues in perinatal medicine. In developed countries, preterm delivery is the cause of about 70% of mortality and 75% of morbidity in the neonatal period, respectively.
Objective:
The aim of this study was to determine the risk factors for preterm labor and the outcomes, in terms of perinatal mortality and morbidity at the time of discharge home, among preterm infants at less than 34 weeks gestation.
Materials And Methods:
A retrospective study was conducted and all infants with a gestational age of 24 to 33 weeks and 6 days who were born from November 1(st), 2011 to March 31, 2012 were enrolled in this study.
Results:
From 1185 preterm infants were born during this period, 475 (40.08%) infants with less than 34 weeks gestational age were included in the study. Our study showed the major obstetrical risk factors for preterm labor were as follows: preeclampsia (21%), premature rupture of membranes (20.3%), abruption of placenta (10%), and idiopathic cases (48.7%). The neonatal mortality rate in less than 34 weeks was 9.05%. Significant perinatal morbidity causesd in less than 34 weeks were as follows: sepsis (46.94%), respiratory distress syndrome (41.47%), patent ductus arteriosus (21.47%), retinopathy of prematurity (3.57%), necrotizing entrocolitis (1.68%), intra-ventricular hemorrhage (9%), and broncho-pulmonary dysplasia (0.84%).
Conclusion:
Preterm birth is associated with adverse perinatal outcome. This situation needs to be improved by directing appropriately increased resources for improving prenatal health services and providing advanced neonatal care.
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