Related Experiment Video
Updated: Mar 28, 2026
09:02
Modeling Hepatitis B Virus Infection in Non-Hepatic 293T-NE-3NRs Cells
Published on: June 5, 2020
8.0K
Hepatitis B virus infection in immigrant populations.
Nicola Coppola1, Loredana Alessio1, Mariantonietta Pisaturo1
1Nicola Coppola, Loredana Alessio, Mariantonietta Pisaturo, Margherita Macera, Evangelista Sagnelli, Department of Mental Health and Public Medicine, Section of Infectious Diseases, Second University of Naples, 80131 Naples, Italy.
World Journal of Hepatology
|January 6, 2016
Summary
Hepatitis B virus (HBV) infection is a global health concern, particularly with immigration. Understanding HBV epidemiology in diverse populations is crucial for prevention and effective management.
Area of Science:
- Hepatology
- Infectious Diseases
- Public Health
Background:
- Hepatitis B virus (HBV) infection is a leading cause of chronic liver disease, cirrhosis, and hepatocellular carcinoma globally.
- High HBV endemicity in certain regions necessitates attention to prevent its spread through immigration to low-endemicity countries.
Purpose of the Study:
- To review the epidemiology, virology, and clinical aspects of HBV infection in immigrant populations.
- To analyze the prevalence and characteristics of HBV in immigrants and their host countries.
- To propose prophylactic measures to curb HBV transmission.
Main Methods:
- Literature review analyzing epidemiological data on HBV infection in immigrants.
- Examination of virological characteristics, including HBV genotypes prevalent in different immigrant groups.
- Assessment of clinical course and treatment challenges for HBsAg-positive immigrants.
Main Results:
- Immigrants from South East Asia and sub-Saharan Africa exhibit the highest prevalence of hepatitis B surface antigen (HBsAg) carriers.
- HBV genotypes in immigrants correlate with their regions of origin (e.g., A/D from Eastern Europe, B/C from Asia, E from Africa).
- Limited literature exists on the clinical outcomes and treatment of HBsAg-positive immigrants.
Conclusions:
- Managing HBV infection in immigrant populations is complex, requiring specialized healthcare structures and personnel.
- Social services, volunteers, and cultural mediators play a vital role in providing comprehensive care and support.
- Preventing HBV spread requires tailored strategies considering the unique epidemiological and clinical profiles of immigrant groups.
Related Concept Videos
01:25Hepatitis
34
Hepatitis is an inflammatory condition of the liver most commonly caused by hepatotropic viruses (A–E), though non-infectious causes such as alcohol and drugs also exist.Hepatitis AHepatitis A virus (HAV) is a non-enveloped RNA virus of the Picornaviridae family. It is primarily transmitted via the fecal-oral route, typically through ingestion of contaminated food or water. After ingestion, HAV enters the bloodstream through the oropharynx or intestinal epithelium and reaches the liver.
34
01:29Pulmonary Tuberculosis I
1.3K
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
1.3K
01:27Cytomegalovirus Disease
19
Cytomegalovirus (CMV) disease is caused by human cytomegalovirus, a double-stranded DNA virus of the Herpesviridae family. While primary CMV infection is often asymptomatic in immunocompetent individuals, the virus can cause severe disease in neonates and immunocompromised patients. CMV is the most common cause of congenital viral infection in the United States, and a major pathogen in solid organ and hematopoietic stem cell transplant recipients.CMV is transmitted via bodily fluids, sexual...
19