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Updated: Mar 27, 2026

Application of Design Aspects in Uniaxial Loading Machine Development
Published on: September 19, 2018
Neutral mechanical alignment: Is it Necessary?
1Mayo Clinic, 200 1st St SW, Rochester, Minnesota 55905, USA.
Abstract:
The cause of dissatisfaction following total knee arthroplasty (TKA) remains elusive. Much attention has been focused on static mechanical alignment as a basis for surgical success and optimising outcomes. More recently, research on both normal and osteoarthritic knees, as well as kinematically aligned TKAs, has suggested that other specific and dynamic factors may be more important than a generic target of 0 ± 3º of a neutral axis. Consideration of these other variables is necessary to understand ideal targets and move beyond generic results.
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