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Updated: Mar 27, 2026

Isolation of Murine Lymph Node Stromal Cells
Published on: August 19, 2014
Innate lymphoid cells: parallel checkpoints and coordinate interactions with T cells
Nicholas D Huntington1, Sabrina Carpentier2, Eric Vivier3
1The Walter and Eliza Hall Institute of Medical Research, and Department of Medical Biology, University of Melbourne, Victoria 3052, Australia; Department of Medical Biology, University of Melbourne, Parkville 3010, Australia.
Abstract:
Protection of epithelial and mucosal surfaces is required for survival. The recent discovery of a diverse array of innate lymphoid cells that lie immediately beneath these surfaces has unexpectedly uncovered an entire defense system distinct from the adaptive system essential to protect these barriers. This multilayered design provides a robust system through coupling of two highly complementary networks to ensure immune protection. Here, we discuss the similarities in the hardwiring and diversification of innate lymphoid cells and T cells during mammalian immune responses.
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