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Updated: Mar 27, 2026

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
[Paranasal sinus mucoceles: About 32 cases]
K Hssaine1, B Belhoucha1, Y Rochdi1
1Service d'ORL et de chirurgie cervico-faciale, CHU Mohammed VI, Marrakech, Maroc.
Introduction:
Mucocele is a pseudo-cystic tumor of the paranasal sinuses. Despite its benign histological nature, it is aggressive towards neighboring structures (orbit and brain). Our aim was to study the epidemiological, clinical, therapeutic, and evolution aspects of this pathology.
Patient And Methods:
We conducted a retrospective study over a period of 9 years on 32 patients operated on and followed for mucocele in our department.
Results:
Mean age was 43.28 years with a sex ratio to 1. Mucoceles were located in the fronto-ethmoid sinus (27 cases), the maxillary sinus (3 cases) and the sphenoid sinus (2 cases). The most common symptoms were periorbital swelling and exophthalmia. CT scan confirmed the diagnosis in the majority of cases. MRI was performed in 3 patients. Surgery consisted in a large marsupialization by endonasal approach in 30 cases, and by a combined approach in two cases. A recurrence was observed in two patients after a mean period of 18 months.
Discussion:
Mucocele is a benign and expansive pseudo-cystic tumor, affecting mostly adults and developing in the paranasal sinuses. Clinical symptoms are not specific. It may reveal itself by ophthalmic or intracranial complications. Diagnosis is based on imaging (CT and MRI). Endonasal surgery has become the gold standard for the treatment of mucoceles and is endowed with low morbidity.
Insights
Paranasal sinus mucoceles are benign tumors that can aggressively affect surrounding structures. Endonasal surgery offers a low-morbidity, gold-standard treatment for these expansive pseudo-cysts.
Area of Science:
- Otolaryngology
- Neurosurgery
- Ophthalmology
Background:
- Mucocele is a benign, expansive pseudo-cystic tumor of the paranasal sinuses.
- Despite its benign nature, it can aggressively invade adjacent orbital and intracranial structures.
- This pathology primarily affects adults, with potential for significant complications.
Purpose of the Study:
- To investigate the epidemiological, clinical, therapeutic, and evolution characteristics of paranasal sinus mucoceles.
- To analyze patient demographics, common symptoms, and diagnostic imaging modalities.
- To evaluate surgical outcomes and recurrence rates following treatment.
Main Methods:
- A 9-year retrospective study involving 32 patients with surgically treated paranasal sinus mucoceles.
- Data collection included patient demographics, clinical presentation, imaging findings, surgical procedures, and follow-up.
- Surgical approaches analyzed were endonasal marsupialization and combined approaches.
Main Results:
- The mean patient age was 43.28 years, with a 1:1 sex ratio.
- Fronto-ethmoid sinus was the most common site (27 cases), followed by maxillary (3) and sphenoid (2).
- Periorbital swelling and exophthalmia were the most frequent symptoms; CT confirmed diagnosis in most cases. Two recurrences were noted after 18 months.
Conclusions:
- Paranasal sinus mucocele is a benign, expansive tumor predominantly affecting adults.
- Clinical symptoms are often non-specific, but ophthalmic or intracranial complications can occur.
- Endonasal surgery is the established gold-standard treatment, demonstrating low morbidity and efficacy.
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