Related Experiment Video
Updated: Mar 27, 2026

Refined Murine Model of Idiopathic Pulmonary Fibrosis
Published on: June 17, 2025
Organizing pneumonia associated with multicentric reticulohistiocytosis
Katsuhiro Yoshimura1, Jun Sato1, Shiro Imokawa1
1Department of Respiratory Medicine Iwata City Hospital Iwata Japan.
Abstract:
Organizing pneumonia (OP) is a clinicopathological entity that occurs idiopathically or in association with several conditions such as connective tissue diseases. Multicentric reticulohistiocytosis (MRH) is a systemic disease characterized by polyarthritis and mucocutaneous lesions, but lung involvement is uncommon. We report a patient with MRH associated with OP. This case may be of interest when considering the pathophysiological mechanisms of both diseases.
Insights
Organizing pneumonia (OP) can occur with connective tissue diseases. This case highlights an unusual association between Multicentric Reticulohistiocytosis (MRH) and OP, offering insights into their shared pathological mechanisms.
Area of Science:
- Pulmonology
- Rheumatology
- Pathology
Background:
- Organizing pneumonia (OP) is a lung disease with idiopathic or secondary causes.
- Multicentric Reticulohistiocytosis (MRH) is a rare systemic disorder affecting joints and skin.
- Pulmonary involvement in MRH is infrequent.
Related Concept Videos
Atypical Pneumonia
Pneumonia I: Introduction
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Pneumonia II: Pathophysiology
Pneumonia IV: Management
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
Cardiomyopathy IV: Restrictive Cardiomyopathy
Pneumonia V: Nursing management and Prevention
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed....

