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Voltage-Dependent Gating: Novel Insights from KCNQ1 Channels

Jianmin Cui1

  • 1Department of Biomedical Engineering, Cardiac Bioelectricity and Arrhythmia Center and Center for the Investigation of Membrane Excitability Disorders, Washington University, St. Louis, Missouri.

Biophysical Journal
|January 9, 2016
PubMed
Summary

Voltage-gated potassium (Kv) channels, like KCNQ1, open pores at multiple voltage sensor activation states. This gating relies on cofactors like PIP2 and ATP, influencing channel function.

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