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Related Concept Videos

The Effect of Aging on Tissues01:19

The Effect of Aging on Tissues

4.1K
Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
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Renewal of Skin Epidermal Stem Cells01:12

Renewal of Skin Epidermal Stem Cells

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The skin is divided into epidermis, dermis, and hypodermis, the skin's outermost, middle, and inner layers. The human epidermal layer regularly undergoes renewal, where old, dead cells are replaced by new cells. Epidermal stem cells or EpiSCs divide and differentiate to restore the lost cells. For the renewal process, some EpiSCs continuously self-renew. In contrast, few others differentiate into transit-amplifying cells, which later form prickle or spinous cells, followed by granular...
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Related Experiment Video

Updated: Mar 27, 2026

Measuring Single-Cell Aging with an Imaging-based Biomarker of Chromatin and Epigenetic Aging
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Measuring Single-Cell Aging with an Imaging-based Biomarker of Chromatin and Epigenetic Aging

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[Methods for measuring skin aging].

M Zieger1,2, M Kaatz3,4

  • 1Klinik für Dermatologie und Allergologie, SRH Wald-Klinikum Gera GmbH, Straße des Friedens 122, 07548, Gera, Deutschland.

Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete
|January 10, 2016
PubMed
Summary
This summary is machine-generated.

Skin aging, driven by intrinsic and extrinsic factors, presents medical and aesthetic challenges. Reliable measurement methods using modern imaging and spectroscopy techniques are crucial for assessing skin aging components.

Keywords:
AgingDiagnostic imagingOptical coherence tomographySkin physiologySpectroscopy

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Area of Science:

  • Dermatology and aging research.
  • Biomedical engineering and imaging science.

Background:

  • Human skin aging is a growing concern with medical, social, and aesthetic implications.
  • Distinguishing between intrinsic (chronological) and extrinsic (environmental) aging is vital.
  • Reliable measurement methods are needed to quantify skin aging.

Purpose of the Study:

  • To highlight the importance of reliable measurement methods for detecting skin aging components.
  • To introduce modern techniques applicable to skin aging assessment.

Main Methods:

  • Direct imaging techniques for visual assessment.
  • Spectroscopy for biochemical and structural analysis.
  • Physiological measurements to assess skin function.

Main Results:

  • Modern techniques offer a wide array of parameters for skin analysis.
  • These methods enable the detection of both intrinsic and extrinsic aging factors.
  • Data from these techniques support various applications in dermatology and cosmetology.

Conclusions:

  • Accurate detection of skin aging components is achievable with current technologies.
  • A combination of imaging, spectroscopy, and physiological measurements provides comprehensive insights.
  • These advancements aid in understanding and managing skin aging.