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Acute chorioamnionitis.

L C Gilstrap1, S M Cox

  • 1Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas.

Obstetrics and Gynecology Clinics of North America
|June 1, 1989
PubMed
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Acute intra-amniotic infection, or chorioamnionitis, is a common pregnancy complication. Prompt antibiotic treatment and delivery are key, with C-sections offering no fetal benefit and increasing maternal risk.

Area of Science:

  • Obstetrics and Gynecology
  • Maternal-Fetal Medicine
  • Infectious Diseases in Pregnancy

Background:

  • Acute intra-amniotic infection (chorioamnionitis) is a frequent obstetric complication.
  • It can lead to substantial maternal and neonatal morbidity.
  • While maternal and term infant mortality are rare, premature infant mortality is often linked to prematurity itself.

Purpose of the Study:

  • To summarize the diagnosis and management of acute intra-amniotic infection.
  • To highlight key treatment strategies and their timing.
  • To clarify the role of Cesarean section in managing this condition.

Main Methods:

  • Diagnosis relies primarily on identifying maternal fever.
  • Treatment involves prompt administration of antibiotics and delivery.

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  • Antibiotic initiation should occur upon diagnosis unless delivery is imminent.

    • Main Results:

    • Maternal mortality is uncommon.
    • Mortality in term infants is rare.
    • Premature infant mortality is likely attributable to prematurity rather than the infection itself.

    Conclusions:

    • Early diagnosis and treatment with antibiotics and delivery are crucial for managing chorioamnionitis.
    • Cesarean section does not provide a specific advantage for the fetus and may increase maternal risks.
    • Management should focus on timely medical intervention rather than surgical delivery unless otherwise indicated.