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Published on: December 6, 2016
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Obstructive sleep apnoea in children with obesity
Rubina Kassim1, Margaret-Anne Harris2, Gary M Leong3
1General Paediatrics, Mater Children's Hospital, South Brisbane, Queensland, Australia.
Journal of Paediatrics and Child Health
|January 11, 2016
Summary
Obese children, particularly Aboriginal/Torres Strait Islander (ATSI) children, have a higher risk of obstructive sleep apnoea (OSA). High-sensitivity C-reactive protein (hs-CRP) levels correlate with OSA severity.
Area of Science:
- Pediatrics
- Sleep Medicine
- Public Health
Background:
- Obstructive sleep apnoea (OSA) is a common condition in obese children.
- Early identification of OSA risk factors can help prioritize sleep studies.
- Obesity is a significant risk factor for OSA in pediatric populations.
Purpose of the Study:
- To identify predictive factors for obstructive sleep apnoea (OSA) in obese children.
- To aid in the prioritization of sleep studies for at-risk pediatric patients.
- To investigate the association between biochemical markers and OSA severity.
Main Methods:
- Retrospective chart review of obese children from weight management and sleep clinics.
- Data collection included demographics, clinical history, examination findings, biochemical markers, and polysomnogram results.
- Statistical analysis to identify significant predictors of OSA.
Main Results:
- 36% of obese children undergoing polysomnography were diagnosed with OSA.
- Obese Aboriginal/Torres Strait Islander (ATSI) children showed a statistically significant higher prevalence of OSA (P = 0.004).
- A significant correlation was found between high-sensitivity C-reactive protein (hs-CRP) and the obstructive event index (OEI) during REM sleep (r = 0.50, P = 0.04).
Conclusions:
- Ethnicity, specifically being ATSI, is a significant factor in OSA risk among obese children.
- hs-CRP levels are significantly correlated with OSA severity, supporting its role as a potential biomarker.
- Other factors like glycosylated haemoglobin and LDL approached statistical significance, warranting further investigation.
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