[Therapy of multiple sclerosis]

Results of clinical trials performed during the last five years by means of immunosuppressive or immunomodulating agents in the treatment of multiple sclerosis are reported (high dose corticosteroids, azathioprine, cyclophosphamide, plasma exchange, linoleic acid, copolymer 1, total lymphoid irradiation, cyclosporine, interferons). The available treatments which may be of value in the clinical practice are discussed.