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A very rare case of eyelid metastasis originating from lung adenocarcinoma
Mehdi Tavakoli1, Mahsan Assadi2, Mohammad Hassan Seifi2
1Ophthalmic Research Center, Shahid Beheshti University of Medical Sciences, Paidarifard St., Pasdaran Ave., Tehran, 16666, Iran. mehditavakolimd@yahoo.com.
Purpose:
To report a very rare eyelid mass confirmed to be a metastasis from lung adenocarcinoma.
Methods:
A 68-year-old man had a two-month history of a large nodule in the right upper eyelid. He was a known case of lung adenocarcinoma since 2 years without a history of systemic metastasis. He underwent further investigations including orbital imaging and biopsy of the lesion.
Results:
Biopsy and immunohistochemical evaluations of the eyelid lesion revealed a moderate to poorly differentiated adenocarcinoma, a similar histology to the lung lesion.
Conclusions:
Metastatic involvement of the eyelids is rarely seen; specifically, those associated with lung adenocarcinoma as the source have been reported extremely rare. Eyelid metastases present with various and non-specific clinical features, and therefore biopsy of suspicious or recurrent lesions is highly recommended to rule out such malignant processes.
