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Generating a Murine Orthotopic Metastatic Breast Cancer Model and Performing Murine Radical Mastectomy
Published on: November 29, 2018
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Curing Metastatic Breast Cancer.
1Stanford University School of Medicine, Stanford, CA gsledge@stanford.edu.
Journal of Oncology Practice
|January 14, 2016
Summary
Metastatic breast cancer is rarely cured, but rare cases of long-term survival suggest cure is possible. This research agenda explores pathways toward achieving cure for more patients with metastatic breast cancer.
Area of Science:
- Oncology
- Cancer Research
Background:
- Metastatic breast cancer is typically viewed as incurable, impacting patient-physician communication.
- While most patients do not achieve long-term remission, notable exceptions exist.
Purpose of the Study:
- To explore the possibility of cure for metastatic breast cancer.
- To outline a research agenda for achieving cure in a larger patient population.
Main Methods:
- Review of existing data on long-term survivors.
- Conceptual framework for future research directions.
Main Results:
- Identification of rare instances of long-term disease-free survival in metastatic breast cancer.
- Suggests that cure, while uncommon, is achievable for some patients.
Conclusions:
- The possibility of cure for metastatic breast cancer warrants further investigation.
- A dedicated research agenda is proposed to advance curative strategies for a broader patient base.
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