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Singapore Cancer Network (SCAN) Guidelines for Systemic Therapy of Colorectal Cancer
Introduction:
The SCAN colorectal cancer systemic therapy workgroup aimed to develop Singapore Cancer Network (SCAN) clinical practice guidelines for systemic therapy for colorectal cancer in Singapore.
Materials And Methods:
The workgroup utilised a modified ADAPTE process to calibrate high quality international evidence-based clinical practice guidelines to our local setting.
Results:
Five international guidelines were evaluated-those developed by the National Comprehensive Cancer Network for colon (2014) and rectal (2014) cancer, the European Society of Medical Oncology for advanced (2012) and early (2013) cancer and the National Institute of Clinical Excellence (2011). Recommendations on systemic therapy in colorectal cancer were produced.
Conclusion:
These adapted guidelines form the SCAN Guidelines 2015 for systemic therapy of colorectal cancer.
Insights
Singapore Cancer Network (SCAN) developed clinical practice guidelines for colorectal cancer systemic therapy. These adapted international evidence-based guidelines aim to improve cancer care in Singapore.
Area of Science:
- Oncology
- Clinical Practice Guidelines
- Evidence-Based Medicine
Background:
- The Singapore Cancer Network (SCAN) established a workgroup to address the need for updated colorectal cancer systemic therapy guidelines.
- Colorectal cancer remains a significant health concern in Singapore, necessitating standardized treatment protocols.
Purpose of the Study:
- To develop Singapore-specific clinical practice guidelines for the systemic therapy of colorectal cancer.
- To adapt high-quality international evidence-based guidelines for the local Singaporean context.
Main Methods:
- A modified ADAPTE process was employed to systematically evaluate and adapt existing international guidelines.
- Five key international guidelines from organizations like NCCN, ESMO, and NICE were assessed.
Main Results:
- The evaluation identified key recommendations for systemic therapy in colorectal cancer.
- Adaptation of international guidelines resulted in a tailored set of recommendations for Singapore.
Conclusions:
- The adapted guidelines have been published as the SCAN Guidelines 2015.
- These guidelines provide a standardized framework for colorectal cancer systemic therapy in Singapore.
