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Updated: Aug 11, 2026

A Combined 3D Tissue Engineered In Vitro/In Silico Lung Tumor Model for Predicting Drug Effectiveness in Specific Mutational Backgrounds
Published on: April 6, 2016
[Predictive significance of parameters of tumor cell proliferation]
Abstract:
Recent publications on prognostic significance of tumour cell proliferation parameters (mitotic index, 3H-thymidine labelling index, cell cycle distributions using DNA-measurements) in certain human tumours are reviewed. Data on acute leukaemia are controversial. In all other haematological and non-haematological malignancies the cell proliferation parameters correlated inversely with survival rate of patients and with the duration of the relapse-free period. Practical application of these data are discussed.
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