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A Cognitive Paradigm to Investigate Interference in Working Memory by Distractions and Interruptions
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Bethesda 2014: improving on a paradigm shift.

D C Wilbur1, R Nayar2

  • 1Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.

Cytopathology : Official Journal of the British Society for Clinical Cytology
|January 16, 2016
PubMed
Summary

The updated Bethesda System manual offers new guidelines for gynecologic cytology reporting, including benign endometrial cells and complex lesion cases. This essential resource enhances diagnostic consistency for clinical, teaching, and research applications worldwide.

Keywords:
Bethesda SystemPap testgynecologic cytology

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Area of Science:

  • Gynecologic Cytopathology
  • Cytopathology Terminology

Background:

  • The Bethesda System for Reporting Cervical Cytology is a standardized framework.
  • Regular updates are crucial to reflect advancements in diagnostic criteria and reporting practices.

Purpose of the Study:

  • To introduce the key changes and expanded content of the third edition of the Bethesda System terminology manual.
  • To highlight its role as a primary reference for standardized gynecologic cytology reporting globally.

Main Methods:

  • Review and summarization of the significant updates in the third edition of the Bethesda manual.
  • Focus on changes in reporting specific cytologic findings and new sections.

Main Results:

  • The manual includes revised guidance for benign endometrial cells and challenging cases (e.g., low-grade squamous intraepithelial lesions with high-grade suspicion).
  • New content features enhanced illustrations, histological comparisons, an expanded reference list, and a chapter on risk-based management.

Conclusions:

  • The third edition of the Bethesda manual provides a comprehensive update for gynecologic cytology.
  • It aims to ensure a uniform and modern approach to reporting for clinical practice, education, and research worldwide.