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Updated: Mar 27, 2026

Author Spotlight: Advancing Understanding of Age-Related Lens Stiffness Changes
Published on: April 5, 2024
The mechanical response of the porcine lens to a spinning test
Matthew A Reilly1, Philipp Martius2, Saurav Kumar1
1Department of Biomedical Engineering, Ohio State University, 270 Bevis Hall, 1080 Carmack Rd, Columbus, OH 43210, United States.
Abstract:
The pig lens has been used as a model for presbyopia as pigs lack accommodative ability. Previous studies using microindentation have indicated that the shear modulus distribution is qualitatively similar to that of the aged human lens and that the lens does not alter its refractive power due to equatorial stretching. A lens spinning test was used to determine whether prior lens stiffness data obtained from a sectioned porcine lens were reliable and whether the testing conditions significantly influence the lens' mechanical properties. The elastic modulus distribution determined for fresh lenses closely matched that measured previously using a microindentation test. Confocal scanning laser microscopy was used to evaluate changes to the lens' structure arising from mechanical stress and following storage for up to one week.

