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Updated: Aug 18, 2026

Focal Ca2+ Transient Detection in Smooth Muscle
Published on: June 29, 2009
Evidence for compartmentation of high energy phosphagens in smooth muscle
Abstract:
Despite the lack of a clear understanding of the exact mechanisms involved, our results show that ATP and PCr in the taenia do not distribute in a manner predicted by the equilibrium of the Lohmann reaction in a single uniform compartment. Our results may be of significance to the understanding of regulation of metabolism and its coordination with the various ATP-dependent cellular functions. This may be particularly relevant to smooth muscle in which oxidative and glycolytic components of metabolism are known to be independently regulated (Lynch and Paul, 1987). Presumably, our results will be of significance for pathophysiological issues such as ischemia of intestine as well as other smooth muscles.
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