Alopecia: evaluation and management
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Updated: Aug 10, 2026

A New Technique for Quantitative Analysis of Hair Loss in Mice Using Grayscale Analysis
Published on: March 9, 2015
1Division of Dermatology, Duke University Medical Center, Durham, North Carolina.
Abstract:
The patient presenting with hair loss may have a primary dermatologic disease, a genetically engineered process, an infectious disease, an underlying systemic illness, a drug reaction, or a psychological disorder. By first dividing the process into one of three categories, scarring, diffuse-nonscarring, or patchy-nonscarring, one then can approach the evaluation in a rational manner. Using the bedside techniques of a hair pull, hair pluck, and microscopic hair examination and directed laboratory tests, one can narrow the differential diagnosis and can recommend directed therapy.
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