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Author Spotlight: Advancements and Challenges in Hepatitis B Virus Detection
Published on: December 15, 2023
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A cost-consequence analysis of hepatitis B screening in an immigrant population
Alessandra Buja1, Diego Martines2, Salvatore Lobello2
1Dipartimento di Medicina Molecolare, Università degli Studi di Padova, Padua, Italy.
Annali Dell'Istituto Superiore Di Sanita
|January 20, 2016
Summary
Screening for Hepatitis B virus (HBV) in migrant populations is cost-effective. This analysis shows HBV screening prevents numerous chronic hepatitis cases, cirrhosis, and deaths over five years.
Area of Science:
- Public Health
- Epidemiology
- Health Economics
Background:
- Hepatitis B virus (HBV) screening in at-risk groups, including migrants, is recognized as a cost-effective public health strategy.
- Local policy-makers require data to guide decisions on implementing HBV screening programs.
Purpose of the Study:
- To assess the cost-consequences of an HBV screening strategy in a specific high-risk population.
- To provide evidence-based information for local and regional policy-makers regarding HBV screening.
Main Methods:
- A cost-consequence analysis was performed using a modeling approach.
- The study cohort comprised adult migrants in Padua province, northern Italy.
- The analysis evaluated outcomes over a five-year period.
Main Results:
- The screening targeted 65,405 migrants, identifying 3,251 HBV infections (prevalence 4.97%).
- Over five years, screening prevented an estimated 565 chronic hepatitis cases, 141 compensated cirrhosis, 9 decompensated cirrhosis, 14 hepatocellular carcinomas, and 12 deaths annually.
- The incremental cost of the screening strategy was €7,974,959, with a cost per life saved of €676,709.
Conclusions:
- The HBV screening strategy demonstrates significant public health benefits by preventing severe liver disease and mortality.
- The findings offer valuable insights for local and regional policy-makers considering HBV screening initiatives for migrant populations.
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