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Updated: Mar 26, 2026

Fluorescence Assays for the Study of Mycobacterium tuberculosis Interaction with the Immune Receptor SLAMF1
Published on: February 28, 2025
Performance indicators of fluorescence microscopy for sputum samples in pulmonary tuberculosis
N Selvakumar1, A Syam Sunder1, M Gomathi Sekar1
1National Institute for Research in Tuberculosis (ICMR), Mayor Sathiyamurthy Road, Chennai 600031, India.
Abstract:
To get insight into the sensitivity of fluorescence microscopy for diagnostic and follow-up sputum samples from pulmonary tuberculosis patients in clinical trials, the yield of smear positivity - among culture positive sputum samples - encountered in diagnostic and follow-up samples was retrospectively analyzed from the data available in a mycobacteriology laboratory in India. The sensitivity of fluorescence microscopy for diagnostic and follow-up samples respectively was found to be 94.3% and 60.7%. With these values as guidelines, the performance of fluorescence microscopy in the treatment of multi-drug resistant tuberculosis under DOTS plus program remains to be monitored and studied.
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