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Related Concept Videos

Primary Lymphoid Organs01:16

Primary Lymphoid Organs

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Primary lymphoid organs are pivotal in the formation, development, and maturation of lymphocytes, the white blood cells that serve as the backbone of our immune system. This crucial function underscores their fundamental role in maintaining our overall health and immunity. The two primary lymphoid organs of prime importance are the red bone marrow and the thymus.
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...
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Pulmonary Tuberculosis III01:31

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Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
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Pulmonary Tuberculosis II01:28

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Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
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Pulmonary Tuberculosis I01:29

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Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
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Pulmonary Hypertension: Classification and Pathogenesis01:30

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Pulmonary hypertension (PH) is a severe health condition in which the mean pulmonary arterial pressure increases to 25 mmHg or more, even when the body is at rest. This high pressure in the blood vessels that transport blood from the heart to the lungs can cause various symptoms, including shortness of breath, can lead to right heart failure, and significantly affect the overall quality of life.
There are various classifications for PH, each relating to different underlying causes and also...
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Secondary Lymphoid Organs01:15

Secondary Lymphoid Organs

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Secondary organs, including lymph nodes, the spleen, and mucosa-associated lymphoid tissue (MALT), work harmoniously to protect us from disease and infection.
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
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Primary Pulmonary Hodgkin Lymphoma.

Shumaila Tanveer1, Ahmed El Damati1, Ayman El Baz1

  • 1Cardiothoracic Surgery Unit, Department of Surgery, King Fahd University Hospital, King Faisal University , Al Khobar.

Rare Tumors
|January 21, 2016
PubMed
Summary

Primary pulmonary Hodgkin lymphoma (PPHL) is a rare condition. Early diagnosis is crucial, emphasizing the need for a broad differential diagnosis in suspected cases.

Keywords:
Primary pulmonary Hodgkin lym-phomanecrotizing pneumonia

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Flow-sorting and Exome Sequencing of the Reed-Sternberg Cells of Classical Hodgkin Lymphoma
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Area of Science:

  • Oncology
  • Pulmonology
  • Pathology

Background:

  • Primary pulmonary Hodgkin lymphoma (PPHL) is an exceptionally rare neoplastic proliferation of lymphocytes within the lung parenchyma.
  • Distinguishing PPHL from other pulmonary conditions can be diagnostically challenging due to its rarity and varied presentations.

Observation:

  • This report details a specific case of PPHL presenting with initial diagnostic uncertainties.
  • The case highlights the complexities encountered during the initial evaluation phase of suspected PPHL.

Findings:

  • Diagnostic concerns arose during the initial assessment, underscoring the importance of considering PPHL in the differential diagnosis.
  • A high index of suspicion is warranted for this rare pulmonary malignancy.

Implications:

  • Accurate and timely diagnosis of PPHL is critical for appropriate patient management and treatment strategies.
  • Raising awareness among clinicians about PPHL can improve diagnostic yield and patient outcomes.