Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Brain Imaging

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Screw-Lock: A Novel Technique to Secure Burr Hole Base Ring in DBS Surgery.

Surgical innovation·2026

Same author

miR-181d coordinates homologous recombination and anti-tumor immune responses in glioblastoma.

iScience·2026

Same author

In-hospital outcomes following fusion for spinal deformity in children with spinal cord injury: Analysis using the National Inpatient Sample.

The journal of spinal cord medicine·2026

Same author

Feedforward miR-181d degradation modulates population variance of methyl-guanine methyl transferase and temozolomide resistance.

Cell reports·2025

Same author

Harnessing ferroptosis to transform glioblastoma therapy and surmount treatment resistance.

Cell death discovery·2025

Same author

Trochlear nerve palsy associated with intracranial aneurysms: Scoping review.

Surgical neurology international·2025

Search research articles

Related Experiment Video

Updated: Mar 26, 2026

Intra-Operative Behavioral Tasks in Awake Humans Undergoing Deep Brain Stimulation Surgery

Intra-Operative Behavioral Tasks in Awake Humans Undergoing Deep Brain Stimulation Surgery

Published on: January 6, 2011

Emerging applications of deep brain stimulation.

Mayur Sharma¹, Vikas Naik, Milind Deogaonkar

¹Neurosurgical Oncology, Cleveland Clinic, Cleveland, OH, USA - drmayursharmaneuro@gmail.com.

Journal of Neurosurgical Sciences

|January 21, 2016

Summary

Deep brain stimulation (DBS) is expanding beyond movement disorders to treat conditions like depression and chronic pain. This review explores emerging DBS applications, surgical targets, and new neuromodulation technologies.

More Related Videos

An Invasive Method for the Activation of the Mouse Dentate Gyrus by High-frequency Stimulation

An Invasive Method for the Activation of the Mouse Dentate Gyrus by High-frequency Stimulation

Published on: June 2, 2018

Analysis of Gene Expression Changes in the Rat Hippocampus After Deep Brain Stimulation of the Anterior Thalamic Nucleus

Analysis of Gene Expression Changes in the Rat Hippocampus After Deep Brain Stimulation of the Anterior Thalamic Nucleus

Published on: March 8, 2015

Related Experiment Videos

Last Updated: Mar 26, 2026

Intra-Operative Behavioral Tasks in Awake Humans Undergoing Deep Brain Stimulation Surgery

Intra-Operative Behavioral Tasks in Awake Humans Undergoing Deep Brain Stimulation Surgery

Published on: January 6, 2011

An Invasive Method for the Activation of the Mouse Dentate Gyrus by High-frequency Stimulation

An Invasive Method for the Activation of the Mouse Dentate Gyrus by High-frequency Stimulation

Published on: June 2, 2018

Analysis of Gene Expression Changes in the Rat Hippocampus After Deep Brain Stimulation of the Anterior Thalamic Nucleus

Analysis of Gene Expression Changes in the Rat Hippocampus After Deep Brain Stimulation of the Anterior Thalamic Nucleus

Published on: March 8, 2015

Area of Science:

Neurosurgery
Neurology
Neuroscience

Background:

Deep brain stimulation (DBS) is a proven treatment for movement disorders like Parkinson's disease.
Its success has spurred interest in applying DBS to other challenging neurological and psychiatric conditions.

Purpose of the Study:

To review the expanding applications of DBS beyond movement disorders.
To discuss the underlying pathophysiology, neural circuits, and surgical targets for these new applications.
To highlight recent technological advancements in neuromodulation.

Main Methods:

Literature review of published studies on DBS for non-movement disorders.
Analysis of pathophysiology and neural circuitry in refractory conditions.
Discussion of current and potential surgical targets for DBS.

Main Results:

DBS is being explored for neuropsychiatric disorders (depression, OCD, addiction), eating disorders (obesity), TBI, PTSD, dementias, and chronic pain.
Understanding of specific neural circuits involved in these conditions is advancing.
New technologies like closed-loop systems and optogenetics are emerging.

Conclusions:

DBS shows promise as a treatment for a wider range of refractory disorders.
Further research into specific targets and advanced techniques is crucial for optimizing DBS efficacy.
Neuromodulation represents a growing frontier in treating complex neurological and psychiatric conditions.