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TNF and ROS Crosstalk in Inflammation

Heiko Blaser1, Catherine Dostert2, Tak W Mak3

  • 1The Campbell Family Cancer Research Institute, Ontario Cancer Institute, University Health Network, Toronto, Ontario, Canada.

Trends in Cell Biology
|January 22, 2016
PubMed
Summary

Tumor necrosis factor (TNF) regulates cell death and immunity. Emerging research highlights TNF's role in controlling reactive oxygen and nitrogen species (ROS/RNS) generation in innate immune cells.

Keywords:
NADPH oxidase (NOX)immunityinflammationnecroptosisreactive oxygen species (ROS)tumor necrosis factor (TNF)

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