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Appropriate indications for positron emission tomography/computed tomography, 2015.

Mariza Vorster1, Alexia Doruyter, Anita Brink

  • 1Department of Nuclear Medicine, Steve Biko Academic Hospital and Faculty of Health Sciences, University of Pretoria, South Africa. mike.sathekge@up.ac.za.

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Summary

These recommendations guide physicians on using 18F-fluorodeoxyglucose (18F-FDG) and non-18F-FDG positron emission tomography/computed tomography (PET/CT) scans. They outline appropriate oncological and non-oncological indications for PET/CT, aiding patient management.

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Area of Science:

  • Medical Imaging
  • Nuclear Medicine
  • Radiochemistry

Background:

  • Positron emission tomography/computed tomography (PET/CT) is a powerful molecular imaging tool.
  • PET/CT integrates functional and morphological data for diagnosis and prognosis.
  • It is widely used for patient-tailored treatment approaches in various medical fields.

Purpose of the Study:

  • To provide recommendations for the appropriate use of 18F-FDG and non-18F-FDG PET/CT.
  • To guide referring physicians on selecting suitable oncological and non-oncological indications for PET/CT.
  • To establish a framework for classifying PET/CT utility (Recommended to Not Recommended).

Main Methods:

  • Development of clinical recommendations based on expert consensus.
  • Definition of specific oncological and non-oncological indications for PET/CT.
  • Categorization of recommendations for each pathology and clinical indication.

Main Results:

  • The recommendations cover diverse applications in oncology, cardiology, neurology, and infection/inflammation.
  • Each indication is classified with a specific recommendation level (1-4).
  • PET/CT is highlighted as a sensitive, accurate, whole-body diagnostic and prognostic tool.

Conclusions:

  • These recommendations aim to optimize the use of PET/CT in clinical practice.
  • They support referring physicians in making informed decisions regarding PET/CT utilization.
  • PET/CT's role in directing and changing patient management is emphasized.