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Related Concept Videos

Heart Failure VI: Adjunct Therapies01:22

Heart Failure VI: Adjunct Therapies

543
Additional therapies for treating patients with heart failure (HF) may include procedural interventions, supplemental oxygen, the management of sleep disorders, and nutritional therapy.Procedural InterventionsImplantable Cardioverter-Defibrillator: For patients at risk of life-threatening arrhythmias due to severe left ventricular dysfunction, an Implantable Cardioverter-Defibrillator (ICD) can detect and terminate these arrhythmias, preventing sudden cardiac death and improving survival rates.
543
Heart Valves01:16

Heart Valves

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The human heart is a complex organ with an intricate system of valves that regulate blood flow. There are two main types of valves: atrioventricular (AV) valves and semilunar valves.
The AV valves prevent the backflow of blood from the ventricles to the atria during ventricular contraction. These valves function with the assistance of the chordae tendineae and papillary muscles. When the ventricles are relaxed, the chordae tendineae are slack, allowing blood to flow from the atria into the...
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Related Experiment Video

Updated: Mar 26, 2026

Implantation of the Syncardia Total Artificial Heart
16:11

Implantation of the Syncardia Total Artificial Heart

Published on: July 18, 2014

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The total artificial heart.

Jason A Cook1, Keyur B Shah1, Mohammed A Quader1

  • 1Pauley Heart Center, Virginia Commonwealth University Medical Center, Richmond, VA, USA.

Journal of Thoracic Disease
|January 22, 2016
PubMed
Summary
This summary is machine-generated.

The total artificial heart (TAH) offers mechanical circulatory support for end-stage heart failure. TAH is an alternative when heart transplants are unavailable or LVADs are unsuitable due to complex conditions.

Keywords:
Total artificial heart (TAH)

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Area of Science:

  • Cardiology
  • Biomedical Engineering
  • Thoracic Surgery

Background:

  • The global burden of cardiovascular disease and heart failure is increasing.
  • The demand for heart transplantation exceeds donor availability.
  • Mechanical circulatory support, including TAH and LVAD, is experiencing exponential growth.

Purpose of the Study:

  • To review the history, indications, and surgical implantation of the total artificial heart (TAH).
  • To discuss post-device management, outcomes, and complications associated with TAH.
  • To explore the future directions and applications of TAH in treating end-stage heart failure.

Main Methods:

  • Review of existing literature on total artificial heart technology.
  • Analysis of clinical data regarding TAH implantation and patient outcomes.
  • Comparative assessment of TAH versus left ventricular assist devices (LVADs).

Main Results:

  • TAH serves as a bridge to transplantation for end-stage biventricular heart failure.
  • TAH is a viable option for patients unsuitable for LVADs due to right ventricular failure or structural issues.
  • The use of TAH as destination therapy is under investigation.

Conclusions:

  • TAH is a critical mechanical circulatory support option for specific end-stage heart failure patients.
  • Advancements in TAH technology and its expanding indications are crucial given donor heart scarcity.
  • Further research into TAH as destination therapy is warranted.