Related Experiment Video
Updated: Mar 26, 2026
10:39
Automated Analysis of Intracellular Phenotypes of Salmonella Using ImageJ
Published on: August 9, 2022
3.6K
Cardiac device infection with Salmonella Blockley
Mark C Manguerra1, Stanley Yancovitz1
1Mount Sinai Beth Israel, New York, NY, USA.
Idcases
|January 22, 2016
Summary
Salmonella Blockley cardiac device infections are rare. This case details a 76-year-old man with an infected implantable cardioverter-defibrillator (ICD) due to S. Blockley, requiring device removal and antibiotics.
Area of Science:
- Infectious Diseases
- Cardiology
- Medical Microbiology
Background:
- Human infections with Salmonella Blockley are rare and typically gastrointestinal.
- Cardiac device infections pose significant clinical challenges.
- Limited literature exists on non-gastrointestinal Salmonella infections.
Purpose of the Study:
- To report the first known case of Salmonella Blockley infection associated with an implantable cardioverter-defibrillator (ICD).
- To describe the clinical presentation, diagnosis, and management of this rare infection.
Main Methods:
- Case report of a 76-year-old male patient with an ICD.
- Clinical presentation: ICD pocket site pain, redness, warmth, and purulent drainage.
- Microbiological analysis: Isolation of Salmonella Blockley from wound, device generator, and leads.
Main Results:
- Salmonella Blockley was identified as the causative agent of the ICD pocket infection.
- The patient underwent ICD device removal and received intravenous ceftriaxone treatment.
- No fever or bacteremia was observed in the patient.
Conclusions:
- This is the first documented case of Salmonella Blockley infection involving an implantable cardioverter-defibrillator.
- Early diagnosis and appropriate management, including device explantation and antibiotic therapy, are crucial for successful outcomes.
- Highlights the potential for rare Salmonella serovars to cause serious device-related infections.
Related Concept Videos
01:25Endocarditis I: Introduction
744
Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
744
01:30Reservoir of Infection
29
Infectious diseases arise from intricate interactions between pathogens and their reservoirs. A reservoir of infection refers to the natural habitat where a pathogen lives, grows, and multiplies, serving as a continual source of infection. Reservoirs are broadly classified as either living or nonliving, and each plays a unique role in disease transmission, significantly influencing public health interventions and control strategies.Humans act as reservoirs for a wide array of pathogens,...
29
01:18Endocarditis III: Medical Management
329
Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
329
01:29Endocarditis IV: Nursing Management
564
Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
564
01:18Bacterial Gastroenteritis
14
Bacterial gastroenteritis, characterized by diarrhea, abdominal cramps, and vomiting, is often caused by ingestion of contaminated food or water and is frequently associated with pathogenic Escherichia coli strains. These microbes exploit two principal mechanisms to inflict disease.Shiga toxin–producing E. coli, also referred to as STEC—notably O157:H7—release Shiga toxins that target ribosomes, blocking protein synthesis. The B subunit of the toxin binds the host glycolipid...
14
01:30Bacterial Signaling
43.0K
Bacterial signaling can occur within bacteria (intracellular) or between bacteria (intercellular). At times, a group of bacteria behaves like a community. To achieve this, they engage in quorum sensing, the perception of higher cell density that causes changes in gene expression. Quorum sensing involves both extracellular and intracellular signaling. The signaling cascade starts with a molecule called an autoinducer (AI). Individual bacteria produce AIs that move out of the bacterial cell...
43.0K