Related Experiment Video
Updated: Aug 27, 2026
13:55
Combined Immunofluorescence and DNA FISH on 3D-preserved Interphase Nuclei to Study Changes in 3D Nuclear Organization
Published on: February 3, 2013
Organization of the Ig VH locus in mice and humans
Immunology Today
|October 1, 1989
Abstract:
In order to assess the contribution of the germline VH gene repertoire to antibody diversity, many groups have studied the evolution and the organization of the immunoglobulin VH gene locus in mice and humans. Here, Ulrich Krawinkel, Thomas Christoph and Thomas Blankenstein review recent data on this subject and discuss the potential influence of gene organization on the activation of the VH gene repertoire during the development of the mammalian immune system.
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