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Identification and Dissection of Diverse Mouse Adipose Depots
Published on: July 11, 2019
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The Infrapatellar Adipose Body: A Histotopographic Study.
Veronica Macchi1, Andrea Porzionato, Gloria Sarasin
1Institute of Human Anatomy, Department of Molecular Medicine, University of Padua, Padua, Italy.
Cells, Tissues, Organs
|January 23, 2016
Summary
The infrapatellar fat pad (IFP) has unique microscopic anatomy, differing from abdominal and knee subcutaneous tissues. Its structure suggests a role in pressure absorption and proprioception in the knee joint.
Area of Science:
- Histology and Ultrastructure
- Human Anatomy
- Biomedical Engineering
Background:
- The infrapatellar fat pad (IFP) is a fibro-adipose tissue near knee joint structures.
- Understanding IFP's microscopic anatomy is crucial for knee biomechanics.
Purpose of the Study:
- To analyze the microscopic anatomy of the IFP.
- To compare IFP histology and ultrastructure with abdominal and knee subcutaneous tissues.
Main Methods:
- Histological and ultrastructural analysis of ten IFP specimens.
- Comparison with subcutaneous adipose tissues from the abdomen and knee.
Main Results:
- IFP exhibits smaller lobule areas and thicker septa than abdominal subcutaneous tissue.
- IFP shows larger lobule areas and thinner septa compared to knee subcutaneous tissue.
- IFP adipocytes have a mean area of 3,708 ± 976 µm² with extensive intercellular space and thick fibrillary sheaths.
Conclusions:
- IFP's structural characteristics suggest a role in absorbing pressure variations during knee movement.
- Extensive nerve distribution indicates a potential mechanoreceptor function for proprioception in the knee joint.

