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Related Concept Videos

Ophthalmic Drug Delivery Systems01:23

Ophthalmic Drug Delivery Systems

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Ophthalmic drug delivery faces major limitations due to poor absorption across the corneal membrane. This process is primarily driven by diffusion and is influenced by two main factors: the physicochemical properties of the drug and tear drainage. Most ophthalmic drugs, such as pilocarpine, epinephrine, atropine, and local anesthetics, are weak bases. They are typically formulated at an acidic pH to enhance chemical stability. However, this leads to high ionization, reducing their ability to...
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Related Experiment Video

Updated: Mar 26, 2026

Author Spotlight: Enhancing Visual Outcomes in Cataract Surgery: A Novel Technique to Prevent Posterior Capsular Opacification Through IOL Rotation
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Injectable suture device for intraocular lens fixation.

Jesse M Smith1, Michael Erlanger1, Jeffrey L Olson1

  • 1From the Rocky Mountain Lions Eye Institute, Department of Ophthalmology, University of Colorado, Aurora, Colorado, USA.

Journal of Cataract and Refractive Surgery
|January 23, 2016
PubMed
Summary
This summary is machine-generated.

A novel surgical technique uses a 24-gauge injector for rapid scleral fixation of posterior chamber intraocular lenses (PC IOLs). This method ensures stable PC IOL positioning, offering a promising approach for aphakic patients.

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Area of Science:

  • Ophthalmology
  • Surgical Techniques
  • Medical Devices

Background:

  • Scleral fixation of posterior chamber intraocular lenses (PC IOLs) is crucial for aphakic eyes.
  • Existing methods can be complex and time-consuming.
  • A new, efficient technique is needed.

Observation:

  • The technique involves inserting a 3-piece PC IOL into the anterior chamber.
  • Sclerotomies are created posterior to the limbus for suture loop delivery.
  • Microforceps guide the IOL haptics through the preformed suture loop.

Findings:

  • The suture loop is tightened around the IOL haptic, securing it to the sclera.
  • Simultaneous fixation and sclerotomy closure are achieved with the double-armed needles.
  • Successful application demonstrated in ex vivo porcine eyes and an aphakic patient, showing quick fixation and stable postoperative positioning.

Implications:

  • Offers a potentially faster and more reliable method for scleral-fixated PC IOL implantation.
  • May reduce surgical time and complexity compared to traditional fixation techniques.
  • Provides a stable solution for patients requiring PC IOL fixation, particularly in complex cases.