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Smoking Does Not Affect Occlusion Rates and Morbidity-Mortality after Pipeline Embolization for Intracranial
A Rouchaud1, W Brinjikji2, H J Cloft2
1From the Departments of Radiology (A.R., W.B., H.J.C., D.F.K.) Rouchaud.Aymeric@mayo.edu aymeric.rouchaud@gmail.com.
AJNR. American Journal of Neuroradiology
|January 23, 2016
Summary
This study found that smoking status did not significantly impact long-term outcomes for patients treated for intracranial aneurysms with the Pipeline Embolization Device. Continued counseling on smoking risks is still advised for all patients.
Area of Science:
- Neurosurgery
- Vascular Surgery
- Interventional Radiology
Background:
- Smoking is a known risk factor for intracranial aneurysms.
- The impact of smoking on flow-diverter treatment outcomes is not well understood.
Purpose of the Study:
- To investigate the effect of smoking status on long-term angiographic and clinical outcomes in patients treated with flow-diverter devices for intracranial aneurysms.
Main Methods:
- Retrospective review of 616 patients with 694 aneurysms treated with the Pipeline Embolization Device.
- Patients stratified into never, current, and former smoker groups.
- Comparison of angiographic and clinical outcomes using statistical analyses, including multivariate analysis.
Main Results:
- Current smokers had smaller mean aneurysm size and lower rates of multiple device use.
- No significant difference in long-term angiographic incomplete occlusion rates between smoking groups.
- Similar odds of major morbidity and neurologic mortality across all smoking groups.
Conclusions:
- Smoking status does not appear to be associated with adverse angiographic or clinical outcomes after Pipeline Embolization Device treatment.
- Despite findings, counseling patients with intracranial aneurysms on the risks of tobacco smoking remains crucial.
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