Guided Tissue Regeneration Using a Barrier Membrane in Endodontic Surgery

Area of Science:

• Endodontics
• Oral Surgery
• Regenerative Medicine

Background:

• Endodontic surgery addresses periapical inflammation via lesion enucleation and root-end filling.
• Guided bone regeneration (GBR) is a potential adjunct to enhance periradicular tissue repair.
• The efficacy of GBR in conjunction with endodontic surgery requires thorough investigation.

Purpose of the Study:

• To review the scientific literature on guided bone regeneration in endodontic surgery.
• To evaluate the effects of GBR on periapical lesion healing.
• To classify studies based on lesion anatomy.

Main Methods:

• Systematic literature review of endodontic surgery and GBR.
• Selection of 14 relevant articles based on titles and abstracts.
• Classification of studies according to lesion characteristics (periapical vs. apico-marginal).

Main Results:

• Eight studies focused on periapical lesions (three through-and-through).
• Six studies addressed apico-marginal lesions.
• Overall, low scientific evidence supports the benefit of GBR in endodontic surgery.

Conclusions:

• Current literature provides limited evidence for the routine use of GBR in endodontic surgery.
• The regenerative benefits of GBR in periapical healing remain largely unproven.
• Further high-quality studies are necessary to determine the role of GBR in endodontic procedures.