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Sensing Conductive Hydrogels for Rapid Detection of Cytokines in Blood
Dong-Sik Shin1,2, Zimple Matharu1,3, Jungmok You1,4
1Department of Biomedical Engineering, University of California, Davis, CA, 95616, USA.
Advanced Healthcare Materials
|January 23, 2016
Abstract:
Conducting polymer hydrogel is fabricated atop gold or ITO electrodes and is functionalized with monoclonal antibodies. Binding of interferon-γ molecules causes redox properties of conductive hydrogel to change in a concentration-dependent fashion without the need for washing or sample handling steps. This conductive hydrogel remains functional in a fouling media such as whole blood.
Keywords:
biosensorsconducting polymer hydrogelscytokine detectionelectrochemical detectionimmunoassays
