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Alzheimer's disease: environmental factors and etiologic hypotheses
1McGill Centre for Studies in Aging, McGill University, Montreal, Quebec, Canada.
Abstract:
A review of published reports on conventional and unconventional viruses, aluminum, neurotoxic metals and trace elements, neurotoxins of biological origin and immune systems, suggest that environmental factors, possibly multiple ones, play a significant role in the etiology of Alzheimer's disease. A complex interaction between genetic predisposition to this illness, natural aging processes, environmental factors over a life-time exposure and pathological alterations of the host immune system is proposed.