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Updated: Mar 26, 2026

The Synthesis, Characterization and Reactivity of a Series of Ruthenium N-triphosPh Complexes
Published on: April 10, 2015
Rhodium-catalyzed selective CH functionalization of NNN tridentate chelating compounds via a rollover pathway
Seung Youn Hong1, Jaesung Kwak2, Sukbok Chang2
1Department of Chemistry, Korea Advanced Institute of Science & Technology (KAIST), Daejeon 305-701, Korea. sbchang@kaist.ac.kr and Center for Catalytic Hydrocarbon Functionalizations, Institute for Basic Science (IBS), Daejeon 305-701, Korea.
Abstract:
Reported herein is the first example of the Rh(NHC)-catalyzed selective bis C-H alkylation of NNN tridentate chelating compounds in reaction with alkenes. The observed excellent site-selectivity can readily be explained by the postulated rollover pathway in the C-H bond activation step. The reaction is highly facile affording bis-alkylated tridentate products in high yields over a broad range of versatile heteroarene substrates and alkene reactants including ethylene gas, thus enabling its applications to be feasible in coordination and synthetic chemistry.
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