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Comparative effectiveness of standard CPR vs active compression-decompression CPR with CardioPump for treatment of
Yahya Kemal Günaydın1, Bora Çekmen2, Nazire Belgin Akıllı1
1Department of Emergency Medicine, Konya Training and Research Hospital, Konya, Turkey.
Insights
Active compression-decompression cardiopulmonary resuscitation (ACD-CPR) using CardioPump did not improve survival rates compared to conventional CPR. However, ACD-CPR showed a lower complication rate in cardiac arrest patients.
Area of Science:
- Emergency Medicine
- Cardiology
- Resuscitation Science
Background:
- High mortality rates persist despite advances in cardiopulmonary resuscitation (CPR).
- Active compression-decompression CPR (ACD-CPR) with CardioPump is an alternative method explored to improve outcomes.
- Investigating novel CPR techniques is crucial for enhancing patient survival.
Purpose of the Study:
- To compare the efficacy of conventional CPR versus ACD-CPR using CardioPump.
- To evaluate differences in restoration of spontaneous circulation, survival rates (1-, 7-, 30-day), and hospital discharge.
- To assess and compare complication rates between the two CPR methods.
Main Methods:
- Prospective, randomized medical device study with a case-control group.
- Inclusion of out-of-hospital and in-hospital cardiac arrest patients (April-September 2015).
- Randomized assignment: conventional CPR on odd days, CardioPump ACD-CPR on even days.
Main Results:
- 181 patients included: 86 (47.5%) conventional CPR, 95 (52.5%) CardioPump ACD-CPR.
- No significant differences observed in spontaneous circulation, discharge, or survival rates (P > .05).
- Conventional CPR group experienced a significantly higher complication rate (P < .001).
Conclusions:
- No evidence supports replacing conventional CPR with CardioPump ACD-CPR.
- ACD-CPR using CardioPump did not demonstrate superiority in improving key survival metrics.
- Conventional CPR resulted in more complications than ACD-CPR with CardioPump.
Background:
Despite all of the studies conducted on cardiopulmonary resuscitation (CPR), the mortality rate of cardiac arrest patients is still high. This has led to a search for alternative methods. One of these methods is active compression-decompression CPR (ACD-CPR) performed with the CardioPump.
Objective:
The differences in the restoration of spontaneous circulation; the 1-, 7-, and 30-day survival rates; and hospital discharge rates between conventional CPR and ACD-CPR performed with CardioPump were investigated. In addition, the differences between the 2 methods with respect to complications were also investigated.
Methods:
Our study was a prospective, randomized medical device study with a case-control group. Cardiac arrest cases brought to our emergency medicine clinic by the 112 emergency ambulances from out of hospital and patients who had developed cardiac arrest inhospital clinics between April 2015 and September 2015 were included in our study. For randomization, standard CPR was performed on odd days of each month, and CPR using CardioPump was performed on the even days of each month.
Results:
A total of 181 patients were included in our study. The number of patients who received conventional CPR was determined as 86 (47.5%), and the number of patients who received CPR using the CardioPump was determined as 95 (52.5%). We did not identify any difference between conventional CPR and CardioPump ACD-CPR with respect to restoration of spontaneous circulation, discharge rates, and the 1-, 7-, and 30-day survival rates. (P=.384, P=.601, P=.997, P=.483, and P=.803, respectively) The complication rate was higher in the patient group that received conventional CPR (P<.001).
Conclusion:
As a result of our study, we did not obtain any evidence supporting the replacement of conventional CPR with ACD-CPR performed using CardioPump.
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