Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Glucose Homeostasis: Regulation of Blood Glucose01:02

Glucose Homeostasis: Regulation of Blood Glucose

5.1K
Carbohydrates consumed through foods are converted into glucose, a crucial energy source for the body. In the prandial state, high blood glucose levels stimulate the secretion of insulin from the pancreas. Insulin inhibits hepatic glucose production and stimulates glucose uptake and metabolism by muscle and adipose tissue. The excess glucose is converted into glycogen and stored in the liver and muscles.
During fasting, when blood glucose levels are low, the pancreas secretes glucagon. it...
5.1K
Glucose Absorption Into the Small Intestine01:26

Glucose Absorption Into the Small Intestine

37.2K
Complex carbohydrates consumed cannot be absorbed into the small intestine in their original form. First, they must be hydrolyzed to a monosaccharide form such as glucose or galactose. These monosaccharides are then transported across the intestinal membrane and into the blood via transcellular transport. The intestinal epithelial cells allow the movement of these monosaccharides with a defined 'entry' through membrane transporter proteins present on their apical membrane and...
37.2K
Glucose Homeostasis: Pancreatic Islets and Insulin Secretion01:27

Glucose Homeostasis: Pancreatic Islets and Insulin Secretion

3.0K
The pancreatic islets comprising only 1%-2% of the volume are highly vascularized and innervated mini-organs. They contain five endocrine cell types, including β cells that secrete insulin, which is synthesized as a single polypeptide chain, preproinsulin, processed to proinsulin, and finally to insulin and C-peptide. This process is complex and regulated, involving the Golgi complex, the endoplasmic reticulum, and the secretory granules of the β cell.
Insulin and C-peptide are...
3.0K
Hormones Regulating Blood Glucose01:16

Hormones Regulating Blood Glucose

8.3K
Insulin is released by beta cells of the pancreas when blood glucose levels are high. It facilitates glucose absorption and utilization in insulin-dependent cells with insulin receptors on their plasma membranes. Insulin promotes glucose uptake by increasing the number of glucose transport proteins in the cell membrane, allowing glucose to enter the cell. As a result, glucose utilization and ATP production are enhanced.
In addition to accelerating glucose uptake and utilization, insulin has...
8.3K
Diabetes Mellitus: Type 2 and Gestational01:22

Diabetes Mellitus: Type 2 and Gestational

5.5K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
5.5K
Hypoglycemia and Glucagon01:15

Hypoglycemia and Glucagon

1.3K
Without prolonged fasting, healthy individuals maintain blood glucose levels above 3.5 mM due to a well-adapted neuroendocrine counterregulatory system that effectively prevents acute hypoglycemia, a potentially life-threatening condition. The primary clinical scenarios for hypoglycemia encompass diabetes treatment, inappropriate production of endogenous insulin or insulin-like substances by tumors, and the use of glucose-lowering agents in non-diabetic individuals. Notably, hypoglycemia in the...
1.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Development and bioactive potential of a nanoemulsion containing bacaba peel extract.

Brazilian journal of biology = Revista brasleira de biologia·2025
Same author

First sexual maturity and type of spawning of the fish Conodon nobilis (Linnaeus, 1758) from the Amazon coast - Brazil.

Brazilian journal of biology = Revista brasleira de biologia·2024
Same author

Potential application of munguba butter in the formulation of nanoemulsified systems.

Brazilian journal of biology = Revista brasleira de biologia·2024
Same author

The potential antioxidant activity of incorporating bacaba (Oenocarpus bacaba Mart.) extract into a nanoemulsion system with baru oil.

Brazilian journal of biology = Revista brasleira de biologia·2023
Same author

Development and stability of intimate soap formulations using Sapindus saponaria L. extract as a natural surfactant.

Brazilian journal of biology = Revista brasleira de biologia·2023
Same author

Gill and hepatic histological alterations in Sciades herzbergii resulting from trace element contamination in the Port of São Luiz, Brazil.

Brazilian journal of biology = Revista brasleira de biologia·2023

Related Experiment Video

Updated: Mar 26, 2026

Glucose-Stimulated Insulin Secretion via Perfusion through the Mice Vasculature with an Intact Pancreas
04:41

Glucose-Stimulated Insulin Secretion via Perfusion through the Mice Vasculature with an Intact Pancreas

Published on: July 25, 2025

1.2K

Juçara pulp supplementation improves glucose tolerance in mice.

L M Oyama1, F P Silva1, J Carnier1

  • 1Departamento de Fisiologia, Escola Paulista de Medicina-Universidade Federal de São Paulo, Rua Botucatu, 862-Vila Clementino, São Paulo, SP Brazil.

Diabetology & Metabolic Syndrome
|January 26, 2016
PubMed
Summary

Juçara (Euterpe edulis Mart) supplementation at 0.5% improved glucose tolerance in mice on high-fat diets. Higher doses (2%) negatively impacted glucose metabolism but reduced inflammation in adipose tissue.

Keywords:
AnthocyaninsEuterpe edulis MartInflammationJuçaraMiceObesity

More Related Videos

Evaluation of Hepatic Glucose Production in a Polycystic Ovary Syndrome Mouse Model
09:44

Evaluation of Hepatic Glucose Production in a Polycystic Ovary Syndrome Mouse Model

Published on: March 5, 2022

3.5K
Study of In Vivo Glucose Metabolism in High-fat Diet-fed Mice Using Oral Glucose Tolerance Test OGTT and Insulin Tolerance Test ITT
08:13

Study of In Vivo Glucose Metabolism in High-fat Diet-fed Mice Using Oral Glucose Tolerance Test OGTT and Insulin Tolerance Test ITT

Published on: January 7, 2018

72.4K

Related Experiment Videos

Last Updated: Mar 26, 2026

Glucose-Stimulated Insulin Secretion via Perfusion through the Mice Vasculature with an Intact Pancreas
04:41

Glucose-Stimulated Insulin Secretion via Perfusion through the Mice Vasculature with an Intact Pancreas

Published on: July 25, 2025

1.2K
Evaluation of Hepatic Glucose Production in a Polycystic Ovary Syndrome Mouse Model
09:44

Evaluation of Hepatic Glucose Production in a Polycystic Ovary Syndrome Mouse Model

Published on: March 5, 2022

3.5K
Study of In Vivo Glucose Metabolism in High-fat Diet-fed Mice Using Oral Glucose Tolerance Test OGTT and Insulin Tolerance Test ITT
08:13

Study of In Vivo Glucose Metabolism in High-fat Diet-fed Mice Using Oral Glucose Tolerance Test OGTT and Insulin Tolerance Test ITT

Published on: January 7, 2018

72.4K

Area of Science:

  • Nutrition Science
  • Metabolic Health
  • Obesity Research

Background:

  • Hyperlipidic and hypercaloric diets promote obesity and adipose tissue dysfunction.
  • Juçara (Euterpe edulis Mart) possesses antioxidant properties that may counteract these effects.
  • Investigating Juçara's impact on diet-induced metabolic disturbances is crucial for preventative strategies.

Purpose of the Study:

  • To evaluate the effects of Juçara pulp on glucose tolerance in mice fed a high-fat, high-calorie diet.
  • To assess the impact of Juçara on adipose tissue inflammatory status.
  • To determine optimal dosage for beneficial effects without adverse outcomes.

Main Methods:

  • Mice were fed control or high-fat, high-calorie diets with varying Juçara concentrations (0.5%, 2%) for 10 weeks.
  • Key metabolic markers (glucose, lipids, insulin, adiponectin) and inflammatory cytokines (TNF-α, IL-6, IL-10) were measured.
  • Oral glucose tolerance tests and catalase activity assays were performed on adipose tissues.

Main Results:

  • 0.5% Juçara improved glycemic response in both normocaloric and high-fat diets.
  • 2% Juçara did not alter body composition on high-fat diets but increased body mass on normocaloric diets.
  • 2% Juçara reduced catalase activity and IL-10 levels in epididymal adipose tissue.

Conclusions:

  • 0.5% Juçara benefits outweigh its macronutrient composition, improving glucose metabolism.
  • 2% Juçara's composition may counteract polyphenol benefits for glucose metabolism but improves adipose tissue inflammation.
  • Juçara dosage is critical; lower doses support metabolic health, while higher doses impact inflammation.